Kaplan-Meier survival data can be used as input data to a Markov model. This article and its associated model show two methods to generate transition probabilities from Kaplan-Meier survival data.
- Represent the empirical survival data with a parametric distribution.
- Use the empirical data directly, by creating a Cumulative Density Function.
Please reference the following attachments:
- Kaplan-Meier Article.pdf
- Kaplan-Meier Survival Data.xlsx
- Markov From Kaplan-Meier Data.trex
Comments
It's a great an example, for more thing, in three state markov mode (Progression free state, Progression state , Death), PFS curves calculate which two state transition probability? So as to OS ?
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