How to include vaccination efficacy in Dynamic Cohort models?
TreeAge recently completed a webinar about Dynamic Cohorts - specifically considering an Infectious Disease model - which can be run as either a Cohort or Microsimulation (Parallel Trials).
The model we used (Dynamic Cohort - Infectious Disease.trex) is based on the SIR model with Births and Deaths. You can find the model in the 2018 version of TreeAge Pro via the Projects View: Example Models > Health Care.
We were asked a question: What is the best way to include vaccination efficacy in the model?
There seems as though there would be a few ways to do this and we thought we would throw this question out to the community.
- Would you include additional Health States?
- Would vaccination efficacy be a constant multiplier of the force of infection?
- Would you model immunity weakening and how?
We welcome all comments on this post. Thank you for your input.
(If you are interested in attending our future webinars, register here).