Restricting microsimulation to DES/Markov nodes
I have a model where I have a decision tree with DES nodes at the leaves (all clones of one DES node). I would like to be able to do a microsimulation of the DES nodes only and use standard EV calculations for the chance nodes, because incremental costs are accrued at all of the leaves, but incremental effectiveness is only accrued at one leaf with low probability of being reached (~ 1%).
I have to run hundreds of thousands, if not millions of trials to get a stable estimate of the ICER, and I would also like to run a PSA!
Any suggestions would be most welcome.